In a Taste Bud the Basal Cells Replace the
Using the Lgr6-EGFP-ires-CreERT2 mouse line we here show that Lgr6 is expressed in cells at the basal area of taste buds in fungiform and circumvallate papillae. Likely are intermediate progenitor cells of taste. Taste Buds In a taste bud the basal cells replace the ____ cells. . RT-PCR shows that Lgr5 and Lgr6 may mark the same. Both express not only Shh but also Prox1 Nakayama et al 2008. Cell lineage tracing studies of mice taste buds identified cells expressing KRT5 and KRT14 as the progenitor cells of TBCs both in the intragemmal basal and perigemmal cells 4546. The lifespan of the cells is short due principally to the damaging effects of temperatures textures and size of foods. The support cells assist and support the gustatory cells in their job. Cells supporting cells and basal cells. Even though the cells of the taste bud undergo constant turnover the structural homeostasis of the bud is maintaine...
